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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM4
All Species:
19.7
Human Site:
S54
Identified Species:
30.95
UniProt:
P33991
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33991
NP_005905.2
863
96558
S54
E
L
Q
P
M
P
T
S
P
G
V
D
L
Q
S
Chimpanzee
Pan troglodytes
XP_528129
863
96543
S54
E
L
Q
P
M
P
T
S
P
G
V
D
L
Q
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535063
929
104136
S120
E
L
Q
P
M
P
T
S
P
G
A
D
L
H
S
Cat
Felis silvestris
Mouse
Mus musculus
P49717
862
96718
P54
L
L
P
M
P
T
S
P
G
A
D
L
Q
S
P
Rat
Rattus norvegicus
NP_387500
862
96552
P54
L
L
P
M
P
T
S
P
G
A
D
L
Q
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515513
863
97108
S54
D
L
Q
P
M
P
T
S
P
G
A
D
M
Q
S
Chicken
Gallus gallus
XP_424376
859
96866
P54
Q
P
L
P
T
S
P
P
A
E
Q
S
P
R
A
Frog
Xenopus laevis
P30664
863
97105
S54
E
L
L
P
M
P
T
S
P
S
G
D
V
Q
S
Zebra Danio
Brachydanio rerio
NP_944595
750
84021
S8
M
S
S
P
S
S
Q
S
R
K
R
D
P
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q26454
866
96592
P56
I
S
L
P
P
T
S
P
G
N
I
S
L
P
A
Honey Bee
Apis mellifera
XP_624670
636
71159
Nematode Worm
Caenorhab. elegans
Q21902
759
84917
A17
Y
Y
Q
E
R
F
F
A
N
D
G
V
P
D
T
Sea Urchin
Strong. purpuratus
XP_801985
910
101460
S96
E
L
P
L
M
P
S
S
P
A
S
G
E
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
Baker's Yeast
Sacchar. cerevisiae
P30665
933
104985
R105
A
S
A
S
G
R
S
R
Y
H
S
D
L
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
87.6
N.A.
94.9
95.1
N.A.
92.4
86.3
85.7
71.3
N.A.
60.1
42.1
28.1
63.3
Protein Similarity:
100
100
N.A.
90
N.A.
97
97.3
N.A.
96.1
93.1
92.9
78.7
N.A.
77.3
54.3
46.9
76.3
P-Site Identity:
100
100
N.A.
86.6
N.A.
6.6
6.6
N.A.
80
6.6
73.3
20
N.A.
13.3
0
6.6
40
P-Site Similarity:
100
100
N.A.
86.6
N.A.
13.3
13.3
N.A.
93.3
26.6
80
26.6
N.A.
33.3
0
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.9
42.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
46.5
62.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
0
7
7
20
14
0
0
0
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
7
14
47
0
7
0
% D
% Glu:
34
0
0
7
0
0
0
0
0
7
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
7
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
0
0
20
27
14
7
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% K
% Leu:
14
54
20
7
0
0
0
0
0
0
0
14
34
0
0
% L
% Met:
7
0
0
14
40
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% N
% Pro:
0
7
20
54
20
40
7
27
40
0
0
0
20
20
14
% P
% Gln:
7
0
34
0
0
0
7
0
0
0
7
0
14
27
0
% Q
% Arg:
0
0
0
0
7
7
0
7
7
0
7
0
0
14
0
% R
% Ser:
0
20
7
7
7
14
34
47
0
7
14
14
0
14
40
% S
% Thr:
0
0
0
0
7
20
34
0
0
0
0
0
0
0
14
% T
% Val:
0
0
0
0
0
0
0
0
0
0
14
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _